4-Methoxybutan-2-amine → 4-[2-[(3-fluorophenyl)amino]-4-pyridinyl]-N-(3-methoxy-1-methylpropyl)-2-pyrimidinamine

Participants

Reaction Steps

The title compound was prepared from 3-methoxy-1-methylpropylamine (i.e., the product of Step B) and 4-(2-chloro-4-pyrimidinyl)-N-(3-fluorophenyl)-2-pyridinamine (i.e., the product of Example 17, Step C) in the same fashion as described in Example 17, Step D to give the title compound as a yellow solid, m.p. 104-106° C.

Provenance & Evidence