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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 913468Generated: October 26, 2026

2,2,2-Trifluoroethyl trifluoromethanesulfonate → 1-(2,2,2-Trifluoroethyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrile

https://huagongshe.com/reaction/913468

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2,2,2-Trifluoroethyl trifluoromethanesulfonateHCID 80366—
Reactant4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 67405449—
Product1-(2,2,2-Trifluoroethyl)-4-(trifluoromethyl)-1H-indole-5-carbonitrileHCID 24984457—

Reaction Steps

Synthesized as described in Example 23 using 4-(trifluoromethyl)-1H-indole-5-carbonitrile and 2,2,2-trifluoroethyl trifluoromethanesulfonate: MS (ES) m/z 293 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08026262B2
Source datasetuspto-grants-2011_09
ORD IDord-bb0ebbedc144463fa63993f1364d1fbd
Source noteuspto-grants-2011_09