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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 913581Generated: October 25, 2026

tert-Butyl bromoacetate → 1,1-Dimethylethyl [4-chloro-5-cyano-2-(trifluoromethyl)-1H-benzimidazol-1-yl]acetate

https://huagongshe.com/reaction/913581

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyl bromoacetateHCID 79177—
Reactant4-chloro-2-(trifluoromethyl)-1H-benzimidazole-5-carbonitrileHCID 67404532—
Product1,1-Dimethylethyl [4-chloro-5-cyano-2-(trifluoromethyl)-1H-benzimidazol-1-yl]acetateHCID 69033757—

Reaction Steps

Synthesized as described in Example 200A from 4-chloro-2-(trifluoromethyl)-1H-benzimidazole-5-carbonitrile and 1,1-dimethylethyl bromoacetate: MS (APCl) m/z 360 (M+1).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08026262B2
Source datasetuspto-grants-2011_09
ORD IDord-ecbc34fbde244caeb86c9af1e5553390
Source noteuspto-grants-2011_09