HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Chloro-4-cyanopyridine → HCID 67398777, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Chloro-4-cyanopyridine | HCID 568638 | — |
| Reactant | Hydrogen chloride-ethyl acetate | HCID 21866389 | — |
| Reactant | 2-({4-[2-(Heptylamino)ethyl]-1,3-thiazol-2-yl}thio)-2-methylpropionic acid tert-butyl ester | HCID 59759312 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | HCID 67398777 | HCID 67398777 | — |
Reaction Steps
A compound obtained using 2-({4-[2-(heptylamino)ethyl]-1,3-thiazol-2-yl}thio)-2-methylpropionic acid tert-butyl ester synthesized in Example 303-2 and 2-chloroisonicotinonitrile as starting materials and by operations similar to those of Example 303-3 and Example 303-4 was dissolved in diethyl ether, and reacted with 4 mol/L hydrochloric acid-ethyl acetate to give the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08026370B2 |
| Source dataset | uspto-grants-2011_09 |
| ORD ID | ord-688f6e522b9e4a4da3d762c12b80a556 |
| Source note | uspto-grants-2011_09 |