反应详情

(4-Propylphenyl)methanol (4.93 g) synthesized in Reference Example 36 was dissolved in carbon tetrachloride (65 mL), triphenylphosphine (9.5 g) was added thereto, and the mixture was heated under reflux for 4 hr. The reaction mixture was concentrated under reduced pressure, and the residue was dissolved in hexane. The insoluble material was filtered off, and the filtrate was evaporated under reduced pressure. The residue was purified by silica gel chromatography (elution solvent; hexane) to give the title compound (2.24 g) as a colorless oil.

1. temperaturethe mixture was heated
2. temperatureunder reflux for 4 hr
3. concentrationThe reaction mixture was concentrated under reduced pressure
4. dissolutionthe residue was dissolved in hexane
5. filtrationThe insoluble material was filtered off
6. customthe filtrate was evaporated under reduced pressure
7. customThe residue was purified by silica gel chromatography (elution solvent; hexane)