Dimethylamine, hydrochloride → HCID 59758875, compound

Participants

Reaction Steps

An operation similar to that of Example 442-1 was performed using 2-[(4-{2-[(5-bromopyrimidin-2-yl)amino]ethyl}-1,3-thiazol-2-yl)thio]-2-methylpropionic acid tert-butyl ester synthesized in Example 162-1 and 4-(chloromethyl)-1-phenyl-1H-pyrazole synthesized in Reference Example 18 as starting materials. An operation similar to that of Example 442-2 was performed (solvent was changed to tert-butanol) using the obtained compound and dimethylamine hydrochloride as starting materials. The obtained compound was subjected to an operation similar to that of Example 442-3 to give the title compound.

Provenance & Evidence