Diethyl Malonate → HCID 22939819, compound

HRID 914646Notes

Reaction equation

HRID 914646 reaction equation
[I:1][C:2]1[CH:25]=[C:24]([I:26])[CH:23]=[C:22]([I:27])[C:3]=1[O:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][C:19](O)=O.C(OCC)(=O)[CH2:29][C:30]([O:32]CC)=[O:31]>>[I:1][C:2]1[CH:25]=[C:24]([I:26])[CH:23]=[C:22]([I:27])[C:3]=1[O:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][CH2:16][CH2:17][CH2:18][CH2:19][CH2:29][C:30]([OH:32])=[O:31]

Participants

3

Reactant 2

HCID 7761Diethyl MalonateHCID 22939811HCID 22939811, compound

Product 1

HCID 22939819HCID 22939819, compound

Procedure

According to the method described in Arch. Pharm. (Weinheim) 328, 271 (1995), addition of two carbon atoms was performed to 15-(2,4,6-triiodophenoxy)pentadecanoic acid by using diethyl malonate to obtain 17-(2,4,6-triiodophenoxy)heptadecanoic acid.

Workup

  1. addition(Weinheim) 328, 271 (1995), addition of two carbon atoms

Sources & evidence

ORD record
ord-b714c76ad01f47cfa0c3dadb7662f22e
Source dataset
uspto-grants-2007_09
Patent number
US07264790B2

Reaction notes

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