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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 914736Generated: October 30, 2026

5-Bromo-2-nitropyridine → HCID 16748110, compound

https://huagongshe.com/reaction/914736

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-2-nitropyridineHCID 817620—
Reactant(1S,4S)-2-Boc-2,5-diazabicyclo[2.2.1]heptaneHCID 11521263—
ProductHCID 16748110HCID 16748110—

Reaction Steps

5-Bromo-2-nitropyridine, prepared as described in (J. Am. Chem. Soc., (1945) 67, 668), and tert-butyl (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate, prepared as described in (J. Med. Chem., (1988) 31, 1598-1611), were coupled according to the procedure of Example 2A to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07265115B2
Source datasetuspto-grants-2007_09
ORD IDord-965b885d41d540a4bdcf38ea63716d96
Source noteuspto-grants-2007_09