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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 914760Generated: October 30, 2026

5-Bromo-3-methylisothiazole → HCID 16749564, compound

https://huagongshe.com/reaction/914760

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-Bromo-3-methylisothiazoleHCID 600959—
Reactant(1S,4S)-2-Boc-2,5-diazabicyclo[2.2.1]heptaneHCID 11521263—
ProductHCID 16749564HCID 16749564—

Reaction Steps

tert-Butyl (1S,4S)-2,5-diazabicyclo[2.2.1]heptane-2-carboxylate, prepared as described in (J. Med. Chem., (1988) 31, 1598-1611) and 5-bromo-3-methylisothiazole, prepared as described in (U.S. Pat. No. 3,840,665) were coupled according to the procedure described in Example 1A to provide the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07265115B2
Source datasetuspto-grants-2007_09
ORD IDord-2d1383404e2f4778b49750d6e47da59f
Source noteuspto-grants-2007_09