Chloroform → 7-Benzyl-6-(hydroxymethyl)-4,7-diazaspiro[2.5]octane-5,8-dione
Reaction equation
[CH2:8]([c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1)[N:15]1[CH:16]([CH2:25][O:26][C:27]([CH3:28])([CH3:29])[CH3:30])[C:17](=[O:24])[NH:18][C:19]2([CH2:20][CH2:21]2)[C:22]1=[O:23].[CH:31]([Cl:32])([Cl:33])[Cl:34].[OH:1][C:2]([C:3]([F:4])([F:5])[F:6])=[O:7]>>[CH2:8]([c:9]1[cH:10][cH:11][cH:12][cH:13][cH:14]1)[N:15]1[CH:16]([CH2:25][OH:26])[C:17](=[O:24])[NH:18][C:19]2([CH2:20][CH2:21]2)[C:22]1=[O:23]Participants
4
Sources & evidence
- ORD record
- ord-41ce0dc5dea2408c80ea02d711555515
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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