Methyl iodide → HCID 69332646, compound

Participants

Reaction Conditions

Reaction Steps

In a sealed tube, iodomethane (0.6 ml) was added to a solution of 6-[5-amino-3-phenyl-6-(4-pyridyl)-2-pyrazinyl]-2-isopropyl-3(2H)-pyridazinone (120 mg) in THF (3 ml) and the mixture was stirred at 25-35° C. for 18 hours. A precipitate was collected by filtration to give 4-[3-amino-6-(1-isopropyl-6-oxo-1,6-dihydro-3-pyridazinyl)-5-phenyl-2-pyrazinyl]-1-methylpyridinium iodide (152 mg).

Provenance & Evidence