HCID 69331890, compound → HCID 69331496, compound

Participants

Reaction Steps

A mixture of 6-(1-ethyl-6-oxo-1,6-dihydro-3-pyridazinyl)-3-[(4-methoxybenzyl)amino]-5-phenyl-2-pyrazinecarboxylic acid (1.02 g) in 1,2-dichlorobenzene (20 ml) was refluxed for 3 hours. The mixture was purified by column chromatography on silica gel eluting with a mixture of n-hexane and EtOAc (40:60 v/v) to give 2-ethyl-6-{5-[(4-methoxybenzyl)amino]-3-phenyl-2-pyrazinyl}-3(2H)-pyridazinone as a solid (783 mg).

Provenance & Evidence