Potassium Carbonate → HCID 21897138, compound

HRID 915160Notes

Reaction equation

HRID 915160 reaction equation
Cl[C:2]1[N:7]=[C:6]([NH:8][C:9]2[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[C:11]([Cl:17])[CH:10]=2)[N:5]=[C:4]([NH:18][CH:19]2[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]2)[N:3]=1.[C:26]([O-])([O-])=[O:27].[K+].[K+]>CO>[CH3:26][O:27][C:2]1[N:7]=[C:6]([NH:8][C:9]2[CH:14]=[CH:13][C:12]([O:15][CH3:16])=[C:11]([Cl:17])[CH:10]=2)[N:5]=[C:4]([NH:18][CH:19]2[CH2:25][CH2:24][CH2:23][CH2:22][CH2:21][CH2:20]2)[N:3]=1

Participants

4

Reactant 2

HCID 11430Potassium CarbonateHCID 218970216-chloro-N-(3-chloro-4-methoxyphenyl)-N'-cycloheptyl-[1,3,5]triazine-2,4-diamine

Product 1

HCID 21897138HCID 21897138, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To 6-chloro-N-(3-chloro-4-methoxyphenyl)-N′-cycloheptyl-[1,3,5] triazine-2,4-diamine (5 g) dissolved in methanol was added K2CO3 (3.2 g) and refluxed for about 6-8 h. TLC was monitored. After the completion of the reaction, the reaction mass was filtered through vacuum and the filtrate was evaporated to yield the title compound. (Wt. 4.7 g Y: 95%)

Workup

  1. temperaturerefluxed for about 6-8 h
  2. customAfter the completion of the reaction
  3. filtrationthe reaction mass was filtered through vacuum
  4. customthe filtrate was evaporated

Sources & evidence

ORD record
ord-e992242086ac459db92fda05a84468e0
Source dataset
uspto-grants-2007_09
Patent number
US07265114B2

Reaction notes

Loading…