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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 915325Generated: October 31, 2026

Sodium Hydroxide → HCID 68874451, compound

https://huagongshe.com/reaction/915325

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantHCID 68873580HCID 68873580—
SolventEthanolHCID 702—
SolventTetrahydrofuranHCID 8028—
ProductHCID 68874451HCID 68874451102.4%

Reaction Steps

Prepared according to Procedure H utilizing ethyl 3-(5-{4-[4-(benzyloxy)-3-chloroanilino]-6-quinazolinyl}-2-furyl)-2-propenoate (0.65 g) and aqueous sodium hydroxide (2M, 4 mL) in THF (8 mL) and ethanol (4 mL) to afford the title compound (0.63 g). Electrospray MS m/z 498 (MH+).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07265123B2
Source datasetuspto-grants-2007_09
ORD IDord-64932a28429c491ba0dd441e4a7e20d8
Source noteuspto-grants-2007_09