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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 915405Generated: October 26, 2026

Lithium Hydroxide → {6-[5-(4-chloro-phenyl)-2-methyl-2H-pyrazol-3-ylmethoxy]-indol-1-yl}-acetic acid

https://huagongshe.com/reaction/915405

Reaction equation

Participants

RoleNameHCIDCharge
ReactantLithium HydroxideHCID 3939—
Reactant{6-[5-(4-chloro-phenyl)-2-methyl-2H-pyrazol-3-ylmethoxy]-indol-1-yl}-acetic acid tert-butyl esterHCID 69282513—
Product{6-[5-(4-chloro-phenyl)-2-methyl-2H-pyrazol-3-ylmethoxy]-indol-1-yl}-acetic acidHCID 69280227—

Reaction Steps

In analogy to the procedure described for example 1 f], {6-[5-(4-chloro-phenyl)-2-methyl-2H-pyrazol-3-ylmethoxy]-indol-1-yl}-acetic acid tert-butyl ester was treated with LiOH to obtain {6-[5-(4-chloro-phenyl)-2-methyl-2H-pyrazol-3-ylmethoxy]-indol-1-yl}-acetic acid as off-white crystals.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07265149B2
Source datasetuspto-grants-2007_09
ORD IDord-82fccfe56f454f1fab96aedcdf64b48a
Source noteuspto-grants-2007_09