HRID915445
反应详情
EQUATION
反应方程式
REACTANTS
反应物
PRODUCTS
生成物
AUXILIARIES
试剂、催化剂与溶剂
PROCEDURE
实验过程
A solution of (6-benzyloxy-4-methyl-indol-1-yl)-acetic acid tert-butyl ester (140 mg, 0.4 mmol) in ethanol (14 ml) was hydrogenated over 10% palladium on charcoal (14 mg) at ambient temperature for 3 h. The catalyst was filtered off, the solvent evaporated under reduced pressure to give 100 mg (0.38 mmol, 96%) of the title compound as brown oil which was used in the next step without further purification.
WORKUP
后处理
- filtrationThe catalyst was filtered off
- customthe solvent evaporated under reduced pressure