HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetonitrile → [2-(2,2,2-trifluoro-ethyl)-5-(4-trifluoromethoxy-phenyl)-2H-pyrazol-3-yl]-acetonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetonitrile | HCID 6342 | — |
| Reactant | 5-chloromethyl-1-(2,2,2-trifluoro-ethyl)-3-(4-trifluoromethoxy-phenyl)-1H-pyrazole | HCID 86600632 | — |
| Catalyst | Tetrabutylammonium Cyanide | HCID 165872 | — |
| Product | [2-(2,2,2-trifluoro-ethyl)-5-(4-trifluoromethoxy-phenyl)-2H-pyrazol-3-yl]-acetonitrile | HCID 86600633 | — |
Reaction Steps
In analogy to the procedure described for example 9 b], 5-chloromethyl-1-(2,2,2-trifluoro-ethyl)-3-(4-trifluoromethoxy-phenyl)-1H-pyrazole was reacted with tetrabutylammonium cyanide in acetonitrile to give [2-(2,2,2-trifluoro-ethyl)-5-(4-trifluoromethoxy-phenyl)-2H-pyrazol-3-yl]-acetonitrile as yellow oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07265149B2 |
| Source dataset | uspto-grants-2007_09 |
| ORD ID | ord-d64685d2c95f4ddea47d637e3e359f93 |
| Source note | uspto-grants-2007_09 |