HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → 4-(3,4-Dichlorophenoxy)-1-piperidinebutanoic acid hydrochloride
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Methyl 4-(3,4-dichlorophenoxy)-1-piperidinebutanoate | HCID 69417722 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Product | 4-(3,4-Dichlorophenoxy)-1-piperidinebutanoic acid hydrochloride | HCID 69420311 | 180% |
Reaction Steps
Methyl 4-(3,4-dichlorophenoxy)-1-piperidinebutanoate (0.48 g) was dissolved in HCl solution (6M, 10 mL) and methanol (1 mL) was added. The reaction mixture was heated under reflux for 8 days. The solvents were evaporated to give the title compound (0.46 g).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07265227B2 |
| Source dataset | uspto-grants-2007_09 |
| ORD ID | ord-3b5aae0d2fa940208c1031a359d17d17 |
| Source note | uspto-grants-2007_09 |