HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → N-benzoyl-N'-[3-[4-(3,4-dichlorophenoxy)-1-piperidinyl]propyl]-sulfamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | 4-(3,4-Dichlorophenoxy)-1-piperidineethanamine | HCID 11358209 | — |
| Reactant | Benzoylsulfamoyl chloride | HCID 11830956 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | N-benzoyl-N'-[3-[4-(3,4-dichlorophenoxy)-1-piperidinyl]propyl]-sulfamide | HCID 69420940 | — |
Reaction Steps
4-(3,4-Dichlorophenoxy)-1-piperidineethanamine (0.16 g) was dissolved in dichloromethane (2 ml) and triethylamine (88 μl) was added. Benzoylsulfamoyl chloride (0.13 g) was added and the solution was stirred for 16 h. The solvent was evaporated and the residue was purified by HPLC (ammonium acetate: acetonitrile 95% to 5% aq) to give the title compound (6 mg).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07265227B2 |
| Source dataset | uspto-grants-2007_09 |
| ORD ID | ord-ecc7985fd6f64511802911b351fe8c2a |
| Source note | uspto-grants-2007_09 |