反应详情

0.928 g (0.0086 mmol) of ethyl chloroformate was added to a mixture of 2.5 g (0.0061 mmol) of 5-(2,4-difluorophenyl)-3-iodo-salicylic acid in 6 ml of benzene and 1.728 g (0.014 mmol) of dimethylaniline. The mixture was stirred at room temperature for 3 hr. Ice and a solution of 2.5 N of HCl were added. It was extracted with dichloromethane and the organic phase was dried over magnesium sulphate. The solvent was evaporated at low pressure and the crude was recrystalized from a chloroform-hexane mixture.

1. extractionIt was extracted with dichloromethane
2. dry with materialthe organic phase was dried over magnesium sulphate
3. customThe solvent was evaporated at low pressure
4. customthe crude was recrystalized from a chloroform-hexane mixture