Potassium Cyanide → HCID 21858375, compound

HRID 915877Notes

Reaction equation

HRID 915877 reaction equation
[CH3:1][C@@:2]1([O:35]C(=O)C2C=CC=CC=2)[C@H:15]([O:16]C(=O)C2C=CC=CC=2)[C@@H:14]([CH2:25][O:26]C(=O)C2C=CC=CC=2)[O:13][C@H:3]1[O:4]C(=O)C1C=CC=CC=1.[C-]#N.[K+]>CO>[CH3:1][C@@:2]1([OH:35])[C@H:15]([OH:16])[C@@H:14]([CH2:25][OH:26])[O:13][CH:3]1[OH:4]

Participants

4

Reactant 2

HCID 9032Potassium CyanideHCID 108755601,2,3,5-Tetra-O-benzoyl-2-C-methyl-beta-D-ribofuranose

Product 1

HCID 21858375HCID 21858375, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a suspension of 2-C-methyl-1,2,3,5-tetra-O-benzoyl-β-D-ribofuranose 1.3, (50 g) in anhydrous MeOH (1000 mL) was added KCN (150 mg) and the mixture was allowed to stir at room temperature under argon for 15 hr during which time all the material dissolved in the solvent and the solution became clear. The solvent was evaporated and the residue was dried under vacuum to deliver 14.9 g of product 7.2.

Workup

  1. dissolutiondissolved in the solvent
  2. customThe solvent was evaporated
  3. customthe residue was dried under vacuum

Sources & evidence

ORD record
ord-abe46f3d71e2464bb9d1a07e0048d853
Source dataset
uspto-grants-2007_09
Patent number
US07268119B2

Reaction notes

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