Methoxyacetic Acid → HCID 136005943, compound

HRID 915932Notes

Reaction equation

[CH:1]1([C:7]2[C:15]3[C:14](=[O:16])[NH:13][C:12]([C:17]4[CH:22]=[CH:21][C:20]([NH:23][C:24](=[O:26])[CH3:25])=[CH:19][C:18]=4[O:27][CH3:28])=[N:11][C:10]=3[N:9]([CH3:29])[N:8]=2)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[CH3:30][O:31]CC(O)=O>>[CH:1]1([C:7]2[C:15]3[C:14](=[O:16])[NH:13][C:12]([C:17]4[CH:22]=[CH:21][C:20]([NH:23][C:24](=[O:26])[CH2:25][O:31][CH3:30])=[CH:19][C:18]=4[O:27][CH3:28])=[N:11][C:10]=3[N:9]([CH3:29])[N:8]=2)[CH2:2][CH2:3][CH2:4][CH2:5][CH2:6]1

Participants

Reactant 2

HCID 12251Methoxyacetic Acid

HCID 136005971HCID 136005971, compound

Product 1

HCID 136005943HCID 136005943, compoundYield 96%

Procedure

The same reaction procedure as in Example 12 was performed, except that the compound obtained in Example 45 was used in place of the compound obtained in Example 6, and methoxyacetic acid was used in place of 4-(4-methyl-1-piperazinyl)benzoic acid. In this manner, 82 g (96%) of the captioned compound was obtained.

Workup

customThe same reaction procedure as in Example 12

Sources & evidence

ORD record: ord-eeddc375401b48af9564a538d464b70f
Source dataset: uspto-grants-2007_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07268128B2

Reaction notes

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