2-Methoxyethylamine → HCID 136333264, compound

HRID 915946Notes

Reaction equation

HRID 915946 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[NH:9][C:10](=[O:24])[C:11]3[C:16]([CH:17]4[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]4)=[N:15][N:14]([CH3:23])[C:12]=3[N:13]=2)=[C:4]([O:25][CH2:26][CH3:27])[CH:3]=1.[CH3:28][O:29][CH2:30][CH2:31][NH2:32]>>[CH:17]1([C:16]2[C:11]3[C:10](=[O:24])[NH:9][C:8]([C:5]4[CH:6]=[CH:7][C:2]([NH:32][CH2:31][CH2:30][O:29][CH3:28])=[CH:3][C:4]=4[O:25][CH2:26][CH3:27])=[N:13][C:12]=3[N:14]([CH3:23])[N:15]=2)[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]1

Participants

3

Reactant 2

HCID 80182-MethoxyethylamineHCID 136005963HCID 136005963, compound

Product 1

HCID 136333264HCID 136333264, compoundYield 31%

Procedure

The same reaction procedure as in Example 27 was performed, except that the compound obtained in Example 85 was used in place of the compound obtained in Example 26, and 2-methoxyethylamine was used in place of N-methylpiperazine. In this manner, 46 mg (31%) of the captioned compound was obtained.

Workup

  1. customThe same reaction procedure as in Example 27

Sources & evidence

ORD record
ord-99e2e632b0e54b119fe682e5576fb42d
Source dataset
uspto-grants-2007_09
Patent number
US07268128B2

Reaction notes

Loading…