2-Methoxyethylamine → HCID 136005811, compound

HRID 915988Notes

Reaction equation

HRID 915988 reaction equation
Br[C:2]1[CH:7]=[CH:6][C:5]([C:8]2[NH:9][C:10](=[O:24])[C:11]3[N:16]([CH:17]4[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]4)[N:15]=[C:14]([CH3:23])[C:12]=3[N:13]=2)=[C:4]([O:25][CH2:26][CH3:27])[CH:3]=1.[CH3:28][O:29][CH2:30][CH2:31][NH2:32]>>[CH:17]1([N:16]2[C:11]3[C:10](=[O:24])[NH:9][C:8]([C:5]4[CH:6]=[CH:7][C:2]([NH:32][CH2:31][CH2:30][O:29][CH3:28])=[CH:3][C:4]=4[O:25][CH2:26][CH3:27])=[N:13][C:12]=3[C:14]([CH3:23])=[N:15]2)[CH2:22][CH2:21][CH2:20][CH2:19][CH2:18]1

Participants

3

Reactant 2

HCID 80182-MethoxyethylamineHCID 136005880HCID 136005880, compound

Product 1

HCID 136005811HCID 136005811, compoundYield 37%

Procedure

The same reaction procedure as in Example 16 was performed, except that the compound obtained in Example 116 was used in place of the compound obtained in Example 15, and methoxyethylamine was used in place of N-methylpiperazine. In this manner, 55 mg (37%) of the captioned compound was obtained.

Workup

  1. customThe same reaction procedure as in Example 16

Sources & evidence

ORD record
ord-3558bd877abe422e8497dd2d5ace9c42
Source dataset
uspto-grants-2007_09
Patent number
US07268128B2

Reaction notes

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