反应详情

温度

20 °C

To a suspension of N-ethyl-N′-[7-(phenylsulfanyl)-1,3-benzothiazol-2-yl]urea (107 mg, 0.32 mmol) in CH2Cl2 (5 mL) was added MCPBA (60 mg, 0.24 mmol, 70%). The reaction mixture was stirred at about 20° C. for about 1.5 hrs. The reaction mixture was then concentrated in vacuo. The crude reaction mixture was purified by flash chromatography on SiO2 (EtOAc/CH2Cl2 10/90). 32 mg (29%) of pure product was isolated. LC/MS 346 (MH+); RP-HPLC RT 12.96 min.

1. concentrationThe reaction mixture was then concentrated in vacuo
2. customThe crude reaction mixture
3. customwas purified by flash chromatography on SiO2 (EtOAc/CH2Cl2 10/90)