2,5-Dimethyl-3-pyrroline → 4-(2,5-dimethyl-2,5-dihydropyrrol-1-yl)naphthalene-1-carbonitrile

HRID 916331Notes

Reaction equation

HRID 916331 reaction equation
[C:1]([C:3]1[C:12]2[C:7](=[CH:8][CH:9]=[CH:10][CH:11]=2)[C:6](F)=[CH:5][CH:4]=1)#[N:2].[CH3:14][CH:15]1[CH:19]=[CH:18][CH:17]([CH3:20])[NH:16]1>>[CH3:14][CH:15]1[CH:19]=[CH:18][CH:17]([CH3:20])[N:16]1[C:6]1[C:7]2[C:12](=[CH:11][CH:10]=[CH:9][CH:8]=2)[C:3]([C:1]#[N:2])=[CH:4][CH:5]=1

Participants

3

Reactant 2

HCID 1010662,5-Dimethyl-3-pyrrolineHCID 27367341-Cyano-4-fluoronaphthalene

Product 1

HCID 117085854-(2,5-dimethyl-2,5-dihydropyrrol-1-yl)naphthalene-1-carbonitrileYield 3.4%

Procedure

The title compound (1 mg, 3% yield) was prepared as described for 196MBT2-4 from 1-cyano-4-fluoronaphthalene (20 mg, 0.117 mmol) and 2,5-dimethyl-2,5-dihydro-1H-pyrrole (45 mg, 0.468 mmol).

Sources & evidence

ORD record
ord-91daea77a886464a8eede0658247147b
Source dataset
uspto-grants-2007_09
Patent number
US07268232B2

Reaction notes

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