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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 916332Generated: October 30, 2026

1,2,3,6-Tetrahydropyridine → 4-(3,6-dihydro-2H-pyridin-1-yl)naphthalene-1-carbonitrile

https://huagongshe.com/reaction/916332

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,2,3,6-TetrahydropyridineHCID 12750—
Reactant1-Cyano-4-fluoronaphthaleneHCID 2736734—
Product4-(3,6-dihydro-2H-pyridin-1-yl)naphthalene-1-carbonitrileHCID 1168729926%

Reaction Steps

The title compound (7 mg, 26% yield) was prepared as described for 196MBT2-4 from 1-cyano-4-fluoronaphthalene (20 mg, 0.117 mmol) and 1,2,3,6-tetrahydropyridine (39 mg, 0.468 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07268232B2
Source datasetuspto-grants-2007_09
ORD IDord-0194ff9666d74041880720a6a098a601
Source noteuspto-grants-2007_09