HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Phenyl-1,3,8-triazaspiro(4.5)decan-4-one → 4-(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-8-yl)naphthalene-1-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Phenyl-1,3,8-triazaspiro(4.5)decan-4-one | HCID 70556 | — |
| Reactant | 1-Cyano-4-fluoronaphthalene | HCID 2736734 | — |
| Product | 4-(4-Oxo-1-phenyl-1,3,8-triaza-spiro[4.5]dec-8-yl)naphthalene-1-carbonitrile | HCID 11610643 | 16% |
Reaction Steps
The title compound (7 mg, 16% yield) was prepared as described for 196MBT2-4 from 1-cyano-4-fluoronaphthalene (20 mg, 0.117 mmol) and 1-phenyl-1,3,8-triazaspiro-[4,5]decan-4-one (108 mg, 0.468 mmol).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07268232B2 |
| Source dataset | uspto-grants-2007_09 |
| ORD ID | ord-d87c77253972499385b131b313129951 |
| Source note | uspto-grants-2007_09 |