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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 916338Generated: October 30, 2026

4-Piperidinecarbonitrile, 4-phenyl- → 1-(4-Cyanonaphthalen-1-yl)-4-phenylpiperidine-4-carbonitrile

https://huagongshe.com/reaction/916338

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Piperidinecarbonitrile, 4-phenyl-HCID 181138—
Reactant1-Cyano-4-fluoronaphthaleneHCID 2736734—
Product1-(4-Cyanonaphthalen-1-yl)-4-phenylpiperidine-4-carbonitrileHCID 692271293%

Reaction Steps

The title compound (1 mg, 3% yield) was prepared as described for 196MBT2-4 from 1-cyano-4-fluoronaphthalene (20 mg, 0.117 mmol) and 4-cyano-4-phenylpiperidine (87 mg, 0.468 mmol).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07268232B2
Source datasetuspto-grants-2007_09
ORD IDord-76b94e93a69a466abc79b076b156f541
Source noteuspto-grants-2007_09