Potassium Bromide → HCID 10587954, compound

HRID 916561Notes

Reaction equation

[CH2:1]([N:5]1[CH:21]=[C:8]2[C:9]3[N:10]([N:13]=[C:14]([C:16]4[O:17][CH:18]=[CH:19][CH:20]=4)[N:15]=3)[CH:11]=[N:12][C:7]2=[N:6]1)[CH2:2][CH2:3]C.[K+].[Br-]>>[CH2:1]([N:5]1[CH:21]=[C:8]2[C:9]3[N:10]([N:13]=[C:14]([C:16]4[O:17][CH:18]=[CH:19][CH:20]=4)[N:15]=3)[CH:11]=[N:12][C:7]2=[N:6]1)[CH2:2][CH3:3]

Participants

Reactant 2

HCID 253877Potassium Bromide

HCID 10493146HCID 10493146, compound2×

Product 1

HCID 10587954HCID 10587954, compound

Procedure

8-Butyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine (Compound 21) yield 50%, pale yellow solid m.p. 245-247° C. (EtOAc-light petroleum); IR (KBr): 1610, 1500 cm−1; 1H NMR (DMSO-d6) δ 0.9 (m, 3H); 1.3 (m, 2H); 1.9 (m, 2H); 4.5 (t. 2H, J=7.2); 6.2 (m, 1H); 7.3 (m, 1H); 8.0 (m, 1H); 8.9 (s, 1H); 9.4 (s, 1H).

Sources & evidence

ORD record: ord-e12b31a878914dab80d3615374b1e503
Source dataset: uspto-grants-2007_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07271171B2

Reaction notes

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