Potassium Bromide → HCID 10587109, compound

HRID 916562Notes

Reaction equation

HRID 916562 reaction equation
[NH2:1][C:2]1[N:7]2[N:8]=[C:9]([C:11]3[O:12][CH:13]=[CH:14][CH:15]=3)[N:10]=[C:6]2[C:5]2=[CH:16][N:17]([CH2:19]C)[N:18]=[C:4]2[N:3]=1.[K+].[Br-]>>[NH2:1][C:2]1[N:7]2[N:8]=[C:9]([C:11]3[O:12][CH:13]=[CH:14][CH:15]=3)[N:10]=[C:6]2[C:5]2=[CH:16][N:17]([CH3:19])[N:18]=[C:4]2[N:3]=1

Participants

3

Reactant 2

HCID 253877Potassium BromideHCID 10659581HCID 10659581, compound2×

Product 1

HCID 10587109HCID 10587109, compound

Procedure

5-Amino-8-ethyl-2-(2-furyl)-pyrazolo[4,3-e]1,2,4-triazolo[1,5-c]pyrimidine (Compound 35) yield 65%,-yellow solid m.p. 249-250° C. (EtOAc-light petroleum); IR (KBr): 3430-2950, 1680, 1655, 1620, 1550, 1450 cm−1; 1H NMR (DMSO-d6) δ 1.46 (t, 2H, J=7); 4.30 (d, 2H, J=7); 6.72 (m, 1H); 7.18 (m, 1H); 7.93 (bs, 2H); 7.93 (s, 1H); 8.62 (s, 1H).

Sources & evidence

ORD record
ord-724d20227f3a4dfa8d28122e03c9482a
Source dataset
uspto-grants-2007_09
Patent number
US07271171B2

Reaction notes

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