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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 916716Generated: November 1, 2026

Methanol → Methyl 2-chloro-4-nitrobenzoate

https://huagongshe.com/reaction/916716

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethanolHCID 887—
ReactantSulfuric AcidHCID 1118—
Reactant2-Chloro-4-nitrobenzoic acidHCID 7448—
ProductMethyl 2-chloro-4-nitrobenzoateHCID 83343—

Reaction Steps

2-Chloro-4-nitrobenzoic acid (50 g, 248 mmol) was subjected to methylation using methanol (500 mL) and H2SO4 (98%, 15 mL) according to the procedure described in the example 66 to obtain the title compound(83)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07271193B2
Source datasetuspto-grants-2007_09
ORD IDord-892ac4fb1d724770b1f3b93a731e4044
Source noteuspto-grants-2007_09