Benzyl Bromide → Piperidinium, 1-methyl-4-oxo-1-(phenylmethyl)-, bromide

HRID 916718Notes

Reaction equation

HRID 916718 reaction equation
[CH3:1][N:2]1[CH2:7][CH2:6][C:5](=[O:8])[CH2:4][CH2:3]1.[Br:9][CH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1>CC(C)=O>[Br-:9].[CH2:10]([N+:2]1([CH3:1])[CH2:7][CH2:6][C:5](=[O:8])[CH2:4][CH2:3]1)[C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1

Participants

4

Reactant 2

HCID 7498Benzyl BromideHCID 740491-Methyl-4-piperidone

Product 1

HCID 10802960Piperidinium, 1-methyl-4-oxo-1-(phenylmethyl)-, bromide

Reagents, catalysts & solvents 1

HCID 180AcetoneSolvent

Procedure

To a solution of 1-methyl-4-piperidinone (15 g, 132.6 mmol) in dry acetone (100 mL) was added 1-bromomethylbenzene (24.9 g, 145 mmol) dropwise. It was stirred for 3 h. The title compound (116) separated which was filtered, washed with dry acetone and dried.

Workup

  1. customThe title compound (116) separated which
  2. filtrationwas filtered
  3. washwashed with dry acetone
  4. customdried

Sources & evidence

ORD record
ord-3d6c656e65b648b3b2584630251f7dc7
Source dataset
uspto-grants-2007_09
Patent number
US07271193B2

Reaction notes

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