Trifluoroacetic acid → HCID 69494565, compound

Participants

Reaction Steps

To 290 mg (0.63 mmol) of 2 was added 6 mL of dichloromethane and 6 mL of trifluoroacetic acid. The reaction mixture was allowed to stir at room temperature for 30 minutes and concentrated under reduced pressure. To the residue was added 40 mL of dichloromethane, which was subsequently concentrated under reduced pressure. The above process of addition of dichloromethane and concentrating under reduced pressure was repeated four more times to give 240 mg (0.59 mmol, 94% yield) of 3 as a thick gum (M+H, 402).

Provenance & Evidence