反应详情

To 290 mg (0.63 mmol) of 2 was added 6 mL of dichloromethane and 6 mL of trifluoroacetic acid. The reaction mixture was allowed to stir at room temperature for 30 minutes and concentrated under reduced pressure. To the residue was added 40 mL of dichloromethane, which was subsequently concentrated under reduced pressure. The above process of addition of dichloromethane and concentrating under reduced pressure was repeated four more times to give 240 mg (0.59 mmol, 94% yield) of 3 as a thick gum (M+H, 402).

1. concentrationconcentrated under reduced pressure
2. additionTo the residue was added 40 mL of dichloromethane, which
3. concentrationwas subsequently concentrated under reduced pressure
4. additionThe above process of addition of dichloromethane
5. concentrationconcentrating under reduced pressure