HuagongsheHuagongshe Chemistry Print Report · For research reference only
(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(3-amino-phenyl)methanone → (4-Amino-7-cyclopropylmethyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(3-amino-phenyl)-methanone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | (4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(3-amino-phenyl)methanone | HCID 11859044 | — |
| Reactant | 4-Chloro-7-(cyclopropylmethyl)-7H-pyrrolo[2,3-d]pyrimidine | HCID 73554645 | — |
| Product | (4-Amino-7-cyclopropylmethyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(3-amino-phenyl)-methanone | HCID 67219076 | — |
Reaction Steps
The title compound was prepared from 4-Chloro-7-cyclopropylmethyl-7H-pyrrolo[2,3-d]pyrimidine by procedures analogous to those described for the preparation of (4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(3-amino-phenyl)-methanone. MS: 308.4 (MH+); HPLC Rf: 4.17 min. (HPLC method 4); HPLC purity: 100%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07271262B2 |
| Source dataset | uspto-grants-2007_09 |
| ORD ID | ord-7daba742139242638ec28355817be6f7 |
| Source note | uspto-grants-2007_09 |