4-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine → (4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(3-amino-phenyl)-methanone

Participants

Role	Name	HCID	Charge
Reactant	4-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidine	HCID 265829	—
Reactant	(4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(3-amino-phenyl)methanone	HCID 11859044	—
Product	(4-Amino-7-methyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(3-amino-phenyl)-methanone	HCID 67219490	—

Reaction Steps

The title compound was prepared from 4-Chloro-7-methyl-7H-pyrrolo[2,3-d]pyrimidin by procedures analogous to those described for the preparation of (4-Amino-7-cyclopentyl-7H-pyrrolo[2,3-d]pyrimidin-5-yl)-(3-amino-phenyl)-methanone. MS: 268.1 (MH+); HPLC Rf: 3.17 min. (HPLC method 4); HPLC purity: 92%.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07271262B2
Source dataset	uspto-grants-2007_09
ORD ID	ord-05b7064c210348dbad9e920be139e1ba
Source note	uspto-grants-2007_09