Dimethylformamide dimethyl acetal → HCID 69417527, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of the ketone product from Step A (6.0 g; 21.3 mmol) in DMF (100 mL) in a dried round bottom flask was added N,N-dimethylformamide dimethyl acetal (11.3 mL; 85.1 mmol) under a N2 atmosphere, and the reaction was stirred at 75° C. for 16 hours. Most of the volatiles were removed in vacuo to afford the crude product as a oil which was used in the next step without further purification.

Provenance & Evidence