Hydrazine hydrate (1:1) → HCID 58961575, compound

HRID 916984Notes

Reaction equation

[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[C:15]([C:16]2[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][CH:17]=2)=[CH:14][C:11]([C:12]#[N:13])=[C:10]([O:23][CH2:24][CH2:25][N:26]2C(=O)C3C(=CC=CC=3)C2=O)[N:9]=1.O.NN>>[NH2:26][CH2:25][CH2:24][O:23][C:10]1[N:9]=[C:8]([C:3]2[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=2[Cl:1])[C:15]([C:16]2[CH:17]=[CH:18][C:19]([Cl:22])=[CH:20][CH:21]=2)=[CH:14][C:11]=1[C:12]#[N:13]

Participants

Reactant 2

HCID 24654Hydrazine hydrate (1:1)

HCID 58961583HCID 58961583, compound

Product 1

HCID 58961575HCID 58961575, compound

Procedure

Using the procedure described in Example 26, the product of Example 134 was reacted with hydrazine hydrate to afford the title compound. MS (electrospray) m/e 384.1 MH+ (Rt=2.8 min LC/MS).

Sources & evidence

ORD record: ord-d464952c959d4a8d96062cadf2dffa35
Source dataset: uspto-grants-2007_09
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US07271266B2

Reaction notes

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