Zincchloride → HCID 68139610, compound

HRID 918044Notes

Reaction equation

HRID 918044 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][NH:8][C:9]([NH:11][C:12]2[CH:17]=[CH:16][C:15]([C:18](=[O:22])[CH2:19][CH2:20][CH3:21])=[CH:14][CH:13]=2)=[O:10])[CH:2]=1.[Cl-:23].[Zn+2:24].[Cl-]>CO>[Cl-:23].[Zn+2:24].[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][NH:8][C:9]([NH:11][C:12]2[CH:17]=[CH:16][C:15]([C:18](=[O:22])[CH2:19][CH2:20][CH3:21])=[CH:14][CH:13]=2)=[O:10])[CH:2]=1.[Cl-:23]

Participants

4

Reactant 2

HCID 3007855ZincchlorideHCID 21522704HCID 21522704, compound

Product 1

HCID 68139610HCID 68139610, compoundYield 63%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

To a solution of 1-(3-pyridylmethyl)-3-(4-butyrylphenyl)urea (2.98 g., 0.01 mole) in 200 ml. of methanol was added a solution of anhydrous zinc chloride (0.68 g., 0.005 mole) in 50 ml. of methanol. After standing overnight the solution was concentrated in vacuo to give 2.3 g. of white solid. This was a 63% yield of 1-(3-pyridylmethyl)-3-(4-butyrylphenyl)urea zinc chloride complex.

Workup

  1. concentrationthe solution was concentrated in vacuo
  2. customto give 2.3 g

Sources & evidence

ORD record
ord-224c27d5b6d349b3b7a725d64060af86
Source dataset
uspto-grants-1976_07
Patent number
US03969357

Reaction notes

Loading…