Zincchloride → HCID 21522707, compound

HRID 918045Notes

Reaction equation

HRID 918045 reaction equation
[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][NH:8][C:9]([NH:11][C:12]2[CH:17]=[CH:16][C:15]([C:18]#[N:19])=[CH:14][CH:13]=2)=[O:10])[CH:2]=1.[Cl-:20].[Zn+2:21].[Cl-]>CO>[Cl-:20].[Zn+2:21].[N:1]1[CH:6]=[CH:5][CH:4]=[C:3]([CH2:7][NH:8][C:9]([NH:11][C:12]2[CH:17]=[CH:16][C:15]([C:18]#[N:19])=[CH:14][CH:13]=2)=[O:10])[CH:2]=1.[Cl-:20]

Participants

4

Reactant 2

HCID 3007855ZincchlorideHCID 20484623HCID 20484623, compound

Product 1

HCID 21522707HCID 21522707, compoundYield 72%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent2×

Procedure

To a solution of 1-(3-pyridylmethyl)-3-(4 -cyanophenyl)urea (2.52 g., 0.01 mole) in 100 ml. of methanol was added anhydrous zinc chloride (0.68 g., 0.005 mole) dissolved in 50 ml. of methanol. A solid suspension formed and after stirring 1 hr. the solid was filtered off and air dried. The product was 2.33 g. which was a 72% yield of 1-(3-pyridylmethyl)-3-(4-cyanophenyl)urea zinc chloride complex.

Workup

  1. dissolutiondissolved in 50 ml
  2. customA solid suspension formed
  3. filtrationthe solid was filtered off
  4. customair dried

Sources & evidence

ORD record
ord-d3c1e40c4b794d29806a4f2ce9679007
Source dataset
uspto-grants-1976_07
Patent number
US03969357

Reaction notes

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