4-Chloro-6-methoxy-2-(trifluoromethyl)quinoline → HCID 21445356, compound

HRID 918180Notes

Reaction equation

HRID 918180 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([O:12][CH3:13])[CH:10]=2)[N:5]=[C:4]([C:14]([F:17])([F:16])[F:15])[CH:3]=1>[Pt]>[CH3:13][O:12][C:9]1[CH:10]=[C:11]2[C:6](=[CH:7][CH:8]=1)[NH:5][CH:4]([C:14]([F:17])([F:15])[F:16])[CH2:3][CH2:2]2

Participants

3

Reactant 1

HCID 218137754-Chloro-6-methoxy-2-(trifluoromethyl)quinoline

Product 1

HCID 21445356HCID 21445356, compound

Reagents, catalysts & solvents 1

HCID 23939PlatinumCatalyst

Procedure

4-Chloro-6-methoxy-2-trifluoromethylquinoline was reduced with platinum on carbon to give 6-methoxy-2-trifluoromethyltetrahydroquinoline.

Sources & evidence

ORD record
ord-c161aa44570e42d8b1a1b85f274d2a8f
Source dataset
uspto-grants-1976_07
Patent number
US03969463

Reaction notes

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