4,6-dichloro-2-(trifluoromethyl)quinoline → HCID 21445338, compound

HRID 918181Notes

Reaction equation

HRID 918181 reaction equation
Cl[C:2]1[C:11]2[C:6](=[CH:7][CH:8]=[C:9]([Cl:12])[CH:10]=2)[N:5]=[C:4]([C:13]([F:16])([F:15])[F:14])[CH:3]=1>[Pt]>[Cl:12][C:9]1[CH:10]=[C:11]2[C:6](=[CH:7][CH:8]=1)[NH:5][CH:4]([C:13]([F:15])([F:14])[F:16])[CH2:3][CH2:2]2

Participants

3

Reactant 1

HCID 27368754,6-dichloro-2-(trifluoromethyl)quinoline

Product 1

HCID 21445338HCID 21445338, compound

Reagents, catalysts & solvents 1

HCID 23939PlatinumCatalyst

Procedure

4,6-Dichloro-2-trifluoromethylquinoline was reduced with platinum on carbon to give 6-chloro-2-trifluoromethyltetrahydroquinoline.

Sources & evidence

ORD record
ord-e363c67ea7714c2e8edb5db892ecd8bf
Source dataset
uspto-grants-1976_07
Patent number
US03969463

Reaction notes

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