Hydrochloric Acid → HCID 53911328, compound

HRID 918367Notes

Reaction equation

HRID 918367 reaction equation
Cl.[Br:2][C:3]1[CH:15]=[CH:14][C:13]2[C:12]3[C:7](=[CH:8][C:9]([Br:16])=[CH:10][CH:11]=3)[CH:6]([C:17]#[N:18])[C:5]=2[CH:4]=1.BrC1C=CC2C3C(=CC(Br)=CC=3)CC=2[C:21]=1[CH:34]=[O:35]>>[CH2:34]([O:35][C:17]([CH:6]1[C:5]2[CH:4]=[C:3]([Br:2])[CH:15]=[CH:14][C:13]=2[C:12]2[C:7]1=[CH:8][C:9]([Br:16])=[CH:10][CH:11]=2)=[NH:18])[CH3:21]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 21520956HCID 21520956, compoundHCID 86733737HCID 86733737, compound

Product 1

HCID 53911328HCID 53911328, compound

Procedure

Dry hydrogen chloride is passed into a solution of 2,7-dibromo-9H-fluorene-9-carbonitrile [obtainable e.g. from the corresponding 2,7-dibromo-9H-fluorene carboxaldehyde (J. Org. Chem., 1944, 9, 155) by oximation and dehydration] by a process analogous to that described in Example 1(a). After working up by a procedure similar to that described in Example 1(a) the product can be used crude or purified before use in Example 2(b) below.

Workup

  1. custompurified before use in Example 2(b) below

Sources & evidence

ORD record
ord-1872f4d683f94a4a879e247730a75952
Source dataset
uspto-grants-1976_07
Patent number
US03971782

Reaction notes

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