反应详情

A solution of 41.8 g of N-nitroso-N-[2-(tetrahydropyran-2-yloxy)ethyl]urea in 200 ml of ether and 100 ml of pentane is added to 450 ml of 1N sodium hydroxide solution at 1°-4°C over a 25 minute period. The solution is stirred for an additional 30 minutes and the layers are separated. The organic layer is dried over sodium hydroxide pellets at 0°C for 5 minutes, and then filtered.

1. customthe layers are separated
2. dry with materialThe organic layer is dried over sodium hydroxide pellets at 0°C for 5 minutes
3. filtrationfiltered