Triethylamine → Ethyl [1-(2-phenyl-1,3-dioxolan-2-yl)ethyl]carbamate

HRID 918386Notes

Reaction equation

HRID 918386 reaction equation
[NH2:1][CH:2]([C:4]1([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[O:8][CH2:7][CH2:6][O:5]1)[CH3:3].C(N(CC)CC)C.Cl[C:23]([O:25][CH2:26][CH3:27])=[O:24]>ClCCl>[C:9]1([C:4]2([CH:2]([NH:1][C:23]([O:25][CH2:26][CH3:27])=[O:24])[CH3:3])[O:5][CH2:6][CH2:7][O:8]2)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 10928Ethyl chloroformateHCID 54506116HCID 54506116, compound

Product 1

HCID 53914466Ethyl [1-(2-phenyl-1,3-dioxolan-2-yl)ethyl]carbamate

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A solution of 2-(1-aminoethyl)-2-phenyldioxolane (20 mmoles), triethylamine (24 mmoles), and ethyl chloroformate (22 (mmoles) in 100 ml of dichloromethane is stirred at 0°C for 2 hours, washed with water, dried, and evaporated to give the title compound.

Workup

  1. washwashed with water
  2. customdried
  3. customevaporated

Sources & evidence

ORD record
ord-c31bdc6bab67495cb1213d0791accece
Source dataset
uspto-grants-1976_07
Patent number
US03971772

Reaction notes

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