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HRID918413

反应详情

EQUATION

反应方程式

HRID 918413 的结构方程式

REACTANTS

反应物

2
结构：[Cl-].[Li+]
HCID433294

Lithium Chloride

ClLi

结构：C=CCO[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CO
HCID68142700

未命名化合物

PRODUCTS

生成物

1
结构：C=CCO[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@H]3[C@@H](O)C[C@]2(C)[C@@]1(O)C(=O)CCl
HCID86733758

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

2
结构：O
溶剂HCID962

Water

H2O

结构：CN(C)C=O
溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

A solution of 16α-allyloxy-11β,17,21-trihydroxypregn-4-ene-3,20-dione, 21-methanesulfonate (4.6 mmoles) in 60 ml of dimethylformamide is refluxed for 1 hour under nitrogen with 5 g of lithium chloride. The solution is cooled, diluted with water and filtered. The solid is dissolved in chloroform, washed with 5% hydrochloric acid, water, dried, and evaporated in vacuo to yield the title compound.

WORKUP

后处理

  1. temperatureThe solution is cooled
  2. filtrationfiltered
  3. dissolutionThe solid is dissolved in chloroform
  4. washwashed with 5% hydrochloric acid, water
  5. customdried
  6. customevaporated in vacuo