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HRID918421

反应详情

EQUATION

反应方程式

HRID 918421 的结构方程式

REACTANTS

反应物

3
结构：CC#N
HCID6342

Acetonitrile

C2H3N

结构：NCCSCc1ncccc1Br
HCID12951527

2-{[(3-Bromopyridin-2-yl)methyl]sulfanyl}ethan-1-amine

C8H11BrN2S

结构：CN=C(NS(=O)(=O)c1ccc(Cl)cc1)SC
HCID22756462

未命名化合物

PRODUCTS

生成物

1
结构：CNC(=NCCSCc1[nH]cnc1C)NS(=O)(=O)c1ccc(Cl)cc1
HCID178485013

未命名化合物

PROCEDURE

实验过程

A solution of 3-bromo-2-((2-aminoethyl)thiomethyl) pyridine (5.0 g) and N-(4-chlorobenzenesulphonyl)-N',S-dimethylisothiourea (5.4 g) in acetonitrile was heated under reflux for 24 hours. Concentration followed by recrystallisation afforded N-(4-chlorobenzenesulphonyl)-N'-methyl-N"-[2-((4-methyl-5-imidazolyl)methylthio)ethyl]guanidine.

WORKUP

后处理

  1. temperatureunder reflux for 24 hours
  2. concentrationConcentration
  3. customfollowed by recrystallisation