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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 918421Generated: October 30, 2026

Acetonitrile → HCID 178485013, compound

https://huagongshe.com/reaction/918421

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetonitrileHCID 6342—
Reactant2-{[(3-Bromopyridin-2-yl)methyl]sulfanyl}ethan-1-amineHCID 12951527—
ReactantN-(4-chlorobenzenesulphonyl)-N',S-dimethylisothioureaHCID 22756462—
ProductHCID 178485013HCID 178485013—

Reaction Steps

A solution of 3-bromo-2-((2-aminoethyl)thiomethyl) pyridine (5.0 g) and N-(4-chlorobenzenesulphonyl)-N',S-dimethylisothiourea (5.4 g) in acetonitrile was heated under reflux for 24 hours. Concentration followed by recrystallisation afforded N-(4-chlorobenzenesulphonyl)-N'-methyl-N"-[2-((4-methyl-5-imidazolyl)methylthio)ethyl]guanidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03971786
Source datasetuspto-grants-1976_07
ORD IDord-f311844384ae44d587b9bd78d43a0960
Source noteuspto-grants-1976_07