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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 918422Generated: November 1, 2026

HCID 20362805, compound → HCID 178484978, compound

https://huagongshe.com/reaction/918422

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 20362805HCID 20362805—
ReactantN-(3,4-dichlorobenzenesulphonyl)-N', S-dimethylisothioureaHCID 22756464—
SolventAcetonitrileHCID 6342—
ProductHCID 178484978HCID 178484978—

Reaction Steps

A solution of 6-methyl-2-((2-aminoethyl)thiomethyl) pyridine (3.7 g) and N-(3,4-dichlorobenzenesulphonyl)-N', S-dimethylisothiourea (6.2 g) in acetonitrile (250 ml) was heated under reflux for 48 hours. Concentration, followed by chromatographic purification on a column of alumina afforded N-(3,4-dichlorobenzenesulphonyl)-N'-methyl-N"-[2-((6-methyl-2-pyridyl)methylthio)ethyl]guanidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS03971786
Source datasetuspto-grants-1976_07
ORD IDord-b5820b28d52b412fbe641d0674413f0c
Source noteuspto-grants-1976_07